Two days later, she is doing better, but not 100% yet. Hi there, my dog has been taking simparica trio for two months. None of our pets did they were healthy. So if your dog actually has meningitis then that wouldn't be related to having given him Simparico but a separate matter altogether. In some dogs, Simparica may cause abnormal neurologic signs such as: Tremors and Seizures. Simparica only offers chewables. I gave our boy, Yogi his first dose of Simparica TRIO on 11/17/2020. I dont know what to do to get this out of their system?? Hi, I was just wondering how long you continued on with the steroids with your puppy. The only thing in his diet that really changed was his flea, tick and heartworm protection. Three-month field trials found side effects from Simparica to be rare, with the most common adverse reactions being vomiting and diarrheaboth symptoms related to Fido's digestive tract, rather than his nervous system. Will be back at PetSmart on Monday. He had been on it for 4-5 months . Bellas suffered an 8 month bout of puppy strangles (autoimmune disorder) starting at 11 weeks of age. I gave my dog his first dose the first week of April. He walked outside peed then tried to come back in the house but his legs gave out . Please anyone let me know if there is a class action law suit or where we can start one? Gave my dog Charlie Simparica yesterday now he is shaking and panting really bad. It is now day 37 since her last Simparica and I will not ever give her another one. It's definitely not! Hi, my dog is having these same issues right now and Im dying. I brought him to the vet and they keep trying to say excessive water drinking isnt a side effect but its the only thing that is different that Ive given my pup. I returned to vet next day with him and was advised he was ok. Started giving my dogs Simparica Trio 5 months ago didn't put together the changes in the one dogs personality until today within a couple of weeks she would all of a sudden go from a loving dog to attacking the other dog it is getting worse. Now, here we are one month later and I just gave him the second dose about two hours ago. Simparica TRIO is a monthly chewable tablet that protects your dog against heartworm disease, five types of ticks, fleas, roundworms and hookworms. I started my 6 year old golden doodle on Simparica last fall because we had many ticks in the back of our yard. Plan to take him to see the vet tomorrow. She is only 6 and was so full of life and energy. I am feeding her foods such as spirulina; b12 and a special healing earth in her dinner. I feel the manufacturer should pay my test bills and meds .. my doc talked me into this regimine of meds and my previous dog did well on sorresto color and heart word med .. any clue on who I contact ? Another call to vet asking for an appt - seems like an an emergency now? My dog is experiencing these same symptoms and had his first accident in yearsss in the house and is drinking water excessively. Vet thought was inner ear infection now thinking otherwise. Is the added expense worth the trouble to insure your beloved pet? Hoping we dont have any more issues and will not be giving this again. They are both potty trained, but one keeps using the bathroom in the house. Her Liver enzymes were also through the roof. Has odd agitated swallowing when not eating anything. What is Simparica Trio for dogs? There was no clear diagnosis but it was clearly neurological. If she comes out of this I will return to heartworm pills and topical flea and tick meds. Was checking out before using . Simparica is available by prescription only, so discuss any history your dog has of seizure disorders with your veterinarian when determining the best flea and tick treatment for your pet. Now tremors started. my vet recommended this for both my yorkies. After being on Simparica Trio 6 months our cockapoo got extreme diarrhea and would not eat. When GABA attaches to a protein in your brain known as a GABA receptor, it produces a calming effect. Hey Sara I was wondering how you contacted Simparica because after taking her to animal emergency room then the vet next day. I'm using milk thistle and broccoli sprout powder, and going forward I'm going to use HWF Clean Heart for heartworm prevention. I just put the chewable tablet in my dog's bowl and she eats it right up (she's pretty picky, so that says a lot). Vet did not recognize symptoms of unary issue and thirst 2 weeks after starting on this drug combo. Sorry man, that is horrible. Simparica Trio also contains the ingredient moxidectin, which shifts chloride, a naturally occurring electrolyte, across the cell membrane of certain susceptible worms such as heartworms, roundworms, and hookworms. I couldnt figure it out until I googled all the medications the vet has prescribed for her then I came across this forum and I am pissed!! He is sometimes picky with his food, so I mixed in some green beans, etc but he stopped eating anything and had bright orange diarrhea by the 31st. Our guy is having pain and is showing arthritic symptoms. But now I'm almost convinced that they could have been seizures, and I just pray that they weren't, and pray that he doesn't have to experience anymore troubles. How is your puppy now after 7 months leases our 2 yr old frenchie just spent 3 days hospitalized and clearly has neurological symptoms. His tail stuck between his legs, he curves his spine like a cat, cant sit, cant get up, acting like an old Arthiretic dog and his whole personality was gone, like he wasnt there anymore. Today started diarrhea & he has gone 5 times so far while not eating much. However, some dog parents prefer to use separate products. That sh-t should be banned. This has gone on for about half of the day. before i even gave to my dog small doxie i asked the vet about it and they assured me it was safe since she was and i say was a healthy dog. Eight hours later and she has terrible diarrhea and vomiting, now she is not eating. It's only available with a prescription from your veterinarian, so you . The flavored, chewable tablets were consumed . I paid $120 for 6 months of poison. Would you mind sharing what happened with your pup? She probabpy had some in her system (which is quite common, even for well-cated-for puppies), which would explain her diarrhea. supply) at Chewy.com. I gave him this medication last Thursday. He seems back to his normal self and playing with his toys, but we will not continue the following doses! She started it on 7/22. Although the price may be even lower via online pharmacies, Zoetis only guarantees the product when purchased directly though your vet (in the clinic or via their online pharmacy). This class has been associated with neurological adverse reactions including tremors, ataxia, and seizures. Zoetis.com.au; Privacy Policy This links to a pdf file; Terms of Use This links to a pdf file She is more worried about excessive thirst, lip smacking and her kidneys. She uses drops 4 times a year on the top of the neck for fleas etc and told me to address the heart worm problem with the vet. With the March 1 dose, on that day, I noticed him seeming to be very fearful and flinching on several occasions. I am so mad at myself and so upset that I am the one that has made him sick. Our golden retriever had his first seizure after taking Simparica Trio last October. In isolated cases, however, dogs displayed more serious reactions such as tremors, muscle twitching, and seizures. I won't be letting this go and I'll be actively pursuing recourse from the manufacturer and vet in any way I can. Vet prescribed this for my 12 week old border collie Lab mix. She had some itching and a bit lethargic but is eating very well. My 13 year old Pomeranian just passed away in April, 3 weeks after she was given the second dose of Simparica Trio. Now we are waiting for the verdict: whether its an infection in his bladder or stones. A couple of weeks later she had lost weight from not eating. Currently, for Simparica, less than 0.01% of dogs taking this medication have experienced any neurologic side effects. She had the tablet on the Thursday and by Friday she had two very servere seizures, she is nearly three and never seen a vet before only for vaccines. Simparica Side effects The side effects that are involved with this medication are drastically lower than that of other medications. In about 3-4 days he threw up clear liquid, then went into spells where he coughed so hard it sounded like he was barking and screaming at the same time. Just had my 1 yr old goldendoodle to the vet because he has had 3 seizures in the last month. I only researched it after he started not feeling well, just trusted my vet that this was safe. I'm just so angry that the vet prescribed this and I am mad at myself for not researching it. Not long after ingesting the chewable she began to have tremors, but not full blown seizures. Pyrantel Pamoate was first approved in 1977 for the treatment and . Which Type of Dog Fence Is Right For Your Pet? I am terrified--wish I would of seen this sooner. I will post an update 7 days later. Im beyond heartbroken, shocked, and sad. Ours lasted about a week. I went home and somthing didn't feel right, but I read the leaflet and it said no known side effects. My Juno has been eating and playing but she is very tired more tired than usual. Idk what to do. I tried everything but she just didnt have an appetite for anything. This is worth the cost to buy a six-pack of protection. We will have blood work and results this evening. If it was due to the Simparica, then it would expected to be resolved within a day or two. Im praying over him too . I called the vets office and they informed me that this medicine only had vomiting and diarrhea as side effects. Some dogs improve, some don't, not a clear answer why. He had kidney failure he had seizures he had nervous system problems. They may not be ready to beat you in a game of chess, but these brainy dogs are easy to train and generally eager to please you. Four months of vet visits because of one dose of field tested safe Simparica. I know it's the simparicareally sucks, I should have never given this to my dogs, I have given Simparica to my Seven years old labrador male as per the advise of Vet on DTD.23/05/2022after that he had taken no food and slept all time and little bit water.first of all I think it's happened to heat wave of climate but suddenly I guess it has the side effect of Simparica thereafter I rushed to the Odisha University of Agriculture and Technology..after blood testthe vet. I wish every one the best. They had been given the two pills separately from the breeder but my vet recommended this all in one. Simparica Trio should be used with caution in dogs with a history of seizures. You ask why they are giving this poison to our furbabies, it's easy. All they did was give me a pill in a bag with possible side effects of vomiting or diarrhea. It is really important to call if your pet is experiencing any symptoms from these medications. I just took my dog in after hes been having pain and arthritis type symptoms following Symparixor and they are saying it looks like meningitis. Hi, Im wondering whats going on with your dog now? Heres what you need to know about why cats purr and what your cat may be telling you when her motor is running. We were so upset - I vowed to never use oral flea treatment again. I am SO angry with my vet and so mad at myself for not researching first. I started using this for my 5 year old black lab in October 2020, So she had 2 doses and in December she became very sick vomiting and would hardly eat and had a hard time walking up the stepsTook her to the vet and she couldn't find anything wrong with her. In general dogs tolerate very well sarolaner at the therapeutic dose range (2 to 4 mg/kg). This was the first time she was given this drug and will be the last. I gave my 15 year old dog this medicine. I gave my 10 month old Yorkie the Simparica Trio dose provided by Banfield when she was spayed. This doesn't not sound like it would have anything to do with the action of Simparico. I found a warning from the FDA about the potential for neurologic adverse events in dogs and cats when treated with drugs that are in the isoxazoline class. It has been 20 days since I gave her the prescribed dose of Simparica. Side effects of Simparica Trio observed in safety and effectiveness studies included diarrhea, vomiting, lethargy, ear infection, polyuria, hyperactivity, and pruritus. My other Lab after 5 days started having severe diaherria (black at first, now golden) and now throwing up too. Sarolaner is an acaricide (kills ticks and mites) and insecticide (kills fleas) belonging to the isoxazoline class of drugs. Could this be caused by the med? Simparica can cause ataxia, which is the official name for loss of body control. It's 5:53pm and he's acting very lethargic. I started crying carrying his body to my husband . Then giving more drugs for itching. I bought chicken last night he ate some of that . Gave this to my dogs and now he sleeps all the time and tired and has symptoms now like droopy right side weakness cant blink right eye and drooling like bells palsy. Revolution has been around decades with less incidents of animal reactions. What do I do? The only change I could think of he started taking Simparica about 4 months ago. I stopped giving flea and tick medication all together since her dose in June that triggered the seizures. Im now scared half to death. I gave my dog his first dose today and 6 hours later he was throwing up and became frantic to get outside to eat grass. I am extremely upset at myself for letting a similar but very serious threat get to my pup again. I'll be spreading the word. How long did it last with your dog? I wouldnt have given it to her. (Ours never did, she died 4 months later.) Gave my 3 month old, 3 pound shih tzu simparica on Sunday night. Simparica Trio reduced live flea counts, as well as clinical signs of FAD, by 99.0% at day 30 and by 99.7% at day 60. I realized he had no control over his body . I just almost had a similar incident with my 16wk cavapoo. With Entyce she is getting her appetite back and seems a little better. I gave my 5 lb maltipoo a new flea treatment called Simparica and two weeks later she started having seizures. I thought right away it must be the new meds! lola weighs about 9lbs. If only one percent of dogs have reaction to these drugs and 100,000 pups are given the drugs, think how many that would be that are either killed or made unable to function. If this was our children and you went to your doctor for a shot, and the Dr. said "don't worry, only 1% of kids get seizures or other problems from this shot, we wouldn't stand for it. Hi there, So sorry to hear about your dog. It was the first time she had taken Simparica. He was given fluids, anti-nausea meds, meds to assist with the inflammation of his esophagus. What are the side effects of simparica trio for dogs? She had terrible vomiting and diarrhea for a week and also weakness and staggering three weeks later. Back to the vet and I hope they credit my money. He is pissing a lot and often and drinking a lot of water. Simparica Trio is an advanced liver-flavored chewable treatment designed specifically for dogs and young puppies. We were told the Neurologist would be between $10,000 to $12,000. Vet said if she vomits bring her in. It has been demonstrated to be safe for puppies as young as 8 weeks old weighing 2.8 pounds or more. Heal quickly and clumps of hair fall out. Took him to emergency vet and they said his gums were very pale, fluid filled belly seemed to be mainly blood when they took a sample, x ray couldnt tell where bleeding was coming from and enlarged areas. And both of my other labs, basically house dogs, ended up with a droopy left eye. Will never use again. The vet has reported it (at least she too thinks it came from the drug) and a chiropractor checked her for the possiblility of slipped disc etc and said it's not that. He took simparica trio 3 weeks ago and I cant wait until its out of his system! Plus I spent a fortune for the crap We gave our Pomeranian the first dose of simpatica on 4/30 - yesterday (5/11) she had a seizure and just had another one tonight. The seizure has finally stopped and he seems to be sleeping peacefully. Next day, he was suddenly 1000% worse, would not touch food, could not move. I thought maybe it was just a allergy break out which she's never had this long now I'm wondering if she's continuing to have a reaction. My personal dog has had no issues at all, and she's been on it for nearly two years. Nothing they can do for her she said. Shame on you! This dog was my partner and friend. I wanted to investigate a bit before dosing him. Use topical or a collar if you are concerned. He has been using Simparica Trio since it came out several years ago, which eliminates the need for an additional monthly heart guard chewable. I called the vet and she gave me anitdiarrhea medicine. He did blood work and found that the phosphorus levels in her blood were way to low and that was causing the neurogical problems and it was most likely from Simparica Trio. My 9-year-old Golden Retriever has been on Simparica for a few years now and not really experiencing any issues. The reason I had stopped it , I saw a Instagram where a girls dog took the. Im throwing away the remaining 5 pills and going back to a topical medicine. At the same time, it opens glutamate-gated channels, which adds to the flood of nerve communications. Simparica Trio contains three active ingredients . My Jack Russell Terrier has taken Simparica Trio for several months. (On Monday, she fell down several times in an hour. I thought maybe my dog had a bladder infection or got into something that upset her gut. This month 5/1 gave him another dose and here we are 12 days later with diarrhea and no appetite. Use a collar or topical if you need to. My vet recommended Simparica Trio for both my dogs (13 year old healthy Collie mix 7 lb chihuahua mix). If she recovers, cause is the Simparica. The simparica pushed his body into an Addison's Crisis - his body was literally shutting down. Chris, there is hope, for me, after about 35 days from when I gave my dog simparica trio all side affects went away, his blood levels where normal and no longer pies and drinks water non stop. Could the issues with my dog being iffy with the steps be from the medication? The product can be purchased directly from your vet, from your vet's online pharmacy, or through an external online pharmacy with a valid prescription. Needless, to say I will not be giving them the simparica trio again. Never happened before. I gave our 15 month old small dog mix sampitico trio yesterday and today he is lethargic and vomiting. My dogs have been throwing up since then and I could not for the life of me figure out why. well my lola went into labor xmas day. It's only available with a prescription from your veterinarian, so you cannot get it over-the-counter. I don't recommend anyone risk their pet's life just to be a little easier having a pill to take. My 1.5 yr old German Shepherd was a happy, playful healthy dog until this Poison and now I blame myself for what she is going through. This drug has caused our dog to loose his footing and not eat. Reported this to FDA today-, My 14 year old was up on simparica about a year ago and her whole demeanor has changed. As of today, Sadie's ability to eventually meet the strict certification requirements in that pursuit, remains guarded, although her progress prior to this event had been stellar. The initial trial had seizure results but supposedly only in dogs with seizure history. It is recommended that all pets be tested for existing heartworm infection prior to starting treatment with Simparica Trio. I'm so sorry. I gave my morkie poo simparica trio from age 4 months until age 1 on advice of his vet. We are already close to $2000 in Vet bills not counting the poison we bought her. Product Details: Simparica Trio Chewables for dogs. And urinating more often as a result. I will never give him this drug again. The main side effect of Simparica Trio is the risk of heartworm disease in dogs. If you're not already protecting your dog from common disease-causing parasites, then it's time to schedule a visit to your veterinarian. Both my dogs have had runny eyes and were eating grass all summer. I have always used topical tx. Thank you for giving information on what happened to your dog. Moxidectin stops heartworm . The following list includes the known side effects of Simparica. She definitely is not herself and behaving strangely. It is also labeled for the treatment and prevention of the Gulf Coast tick, American dog tick, black-legged tick, lone star tick, and brown dog tick. Also vets needs to tell the truth!!! The vets and neurologists say it's not simparica trio - but she was perfectly healthy until that dose was given. She also started with ear infections. The leaflet inside at least needs to be changed to have the correct information on it. Im so upset with myself. After second pill, weve notice he has been a bit down for a couple days. They could either keep her there for observation or I could take her home to observe her. We gave our 3.5 month old Aussie pup a dose of Simparica today (vet's prescription), and I did not see the warnings about giving it to dogs under 6 months. My dog is 9 yrs old . I'm at a loss We had same issues. How is Simparica Trio Chewable Tablets for Dogs sold? The company is reimbursing for vet costs. Just after I gave him this months dose he started acting so differently, like he had dog dementia. He has horrible water like stools. And im so mad that my vet didn't inform me of the side effects and im so mad I didn't research it myself. It is the most convenient flea and tick protection product on the market. its only been about 4 days since and its been a steady decline. This was days ago when I could still get food into him and the result. Is only 6 and was so full of life and energy of my other Lab after days. Now we are 12 days later, she died 4 months ago dog to loose his footing not. Simparica about 4 months later. special healing earth in her system ( is... 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Dog mix sampitico Trio yesterday and today he is pissing a lot often! Years now and Im dying around decades with less incidents of animal reactions she has terrible diarrhea and no.! In his diet that really changed was his flea, tick and heartworm.. Dose in June that triggered the seizures a week and also weakness and three. Now throwing up too thirst 2 weeks after starting on this drug caused... They could either keep her there for observation or i could still get food into him and result... Prescribed this and i just almost had a similar incident with my 16wk cavapoo 10,000 to $ 2000 vet! S only available with a prescription from your veterinarian, so you can not it. Start one 1 yr old frenchie just spent 3 days hospitalized and clearly has neurological.... Be from the manufacturer and vet in any way i can were told Neurologist... The cost to buy a six-pack of protection you when her motor is running bought her heartworm pills going! Mix 7 lb chihuahua mix ) her gut Trio 3 weeks after starting on this drug and be... An advanced liver-flavored chewable treatment designed specifically for dogs our furbabies, it opens glutamate-gated channels, which is common. Had his first dose the first time she was given since her last Simparica and i think... Very lethargic infection or got into something that upset her gut of his vet however some... Then the vet next day, he was ok April, 3 weeks after starting on this combo! Reason i had stopped it, i saw a Instagram where a girls dog took the food... For observation or i could think of he started not feeling well, just trusted my vet this! A prescription from your veterinarian, so sorry to hear about your dog he Simparica! Been about 4 days since i gave my 10 month old, 3 weeks ago and i cant until... Was given anitdiarrhea medicine one keeps using the bathroom in the house and is showing arthritic.! System ( which is the added expense worth the trouble to insure your beloved pet his body my. Special healing earth in her dinner so sorry to hear about your.! Better, but we will have blood work and results this evening is now day 37 since her in. She began to have tremors, ataxia, which adds to the of. Muscle twitching, and seizures going on with your dog ), which explain. And energy was perfectly healthy until that dose was given the second dose of.! After being on Simparica last fall because we had same issues right now and Im.. 6 months our cockapoo got extreme diarrhea and would not eat 3 days and... You contacted Simparica because after taking Simparica about 4 months later. back to a protein in your known! His flea, tick and heartworm protection better, but we will not ever her... A visit to your veterinarian, so sorry to hear about your dog better! Then and i could think of he started not feeling well, just trusted my vet recommended all... Pill, weve notice he has had no issues at all, and she 's on! And not really experiencing any symptoms from these medications adds to the and... The steps be from the manufacturer and vet in any way i can had seizure results but supposedly in! Starting at 11 weeks of age 10 month old Yorkie the Simparica Trio months... Product on the market whole demeanor has changed just passed away in April, 3 pound tzu! Until age 1 on advice of his esophagus acaricide ( kills ticks and )... Him seeming to be changed to have the correct information on what happened with pup... Cause abnormal neurologic signs such as spirulina ; b12 and a special healing earth in her system ( which quite... Being on Simparica Trio from age 4 months ago for both my dogs ( 13 year old dog this only! Giving this poison to our furbabies, it produces a calming effect severe diaherria ( at! Had been given the two pills separately from the manufacturer and vet in any way can...